ID: 21432
Meeting / Value in Health Info: ISPOR 14th Annual International Meeting
Orlando, FL, USA
May, 2009
Code: PMC15
Disease: Multiple Diseases/No Specific Disease
Topic: Conceptual Papers (CP)
Topic Subcategory: Cost Studies including CE/CB/CU, resources use and productivity (CS)
Title: EVALUATING AN ONLINE FREEWARE CALCULATOR FOR A COST EFFECTIVENESS MODEL TO ASSESS THE IMPACT OF MEDICATION COMPLIANCE
Author(s):

William F McGhan, PharmD, PhD, Professor of Pharmacy & Health Policy, Vincent J Willey, PharmD, Associate Professor of Pharmacy, Andrew M. Peterson, PharmD, Chair, Department of Pharmacy Practice and Pharmacy Administration, Amruta A. Manke, BS, Graduate Student, Divyesh D. Patel, BS, Graduate Student, Mayank R. Ajmera, BS, Graduate StudentUniversity of the Sciences, Philadelphia, PA, USA

Content:

OBJECTIVES : To evaluate an online freeware, cost-effectiveness calculator that generates and plots estimations related to the impact of medication compliance on life years gained, drug expenditures, and total health care cost. METHODS An online calculator and plotter were developed that estimates the impact of patient compliance on the cost-effectiveness of therapy. This model was based on a more complex compliance model description published by Hughes D. et al. The online data calculations were compared with an MS Excel spreadsheet model. The cost effectiveness calculator is freely available through www.healthstrategy.com. Data inputs that can be modified include (for compliant and non-compliant separately): utility (QoL), annual drug costs, annual non-drug costs, percent deaths per year, total number of study years, and number of initial patients. RESULTS The online calculator runs on most personal computer operating systems with javascript enabled browsers such as Internet Explorer, Firefox, Opera, or Safari. For twenty different levels compliance (from 0 to 100 percent) this Internet tool outputs and plots results for: total QALYs, life years, total health care costs, non-drug expenditures and total health care expenditures. For 100 patients over 5 years, the MS Excel spreadsheet data versus the online calculated values compared as follows for 50% compliance: QALYs (372 vs. 375), Life Years:(451 vs. 450), drug costs:($23,750 vs. $23,750), non-drug costs:($228,750 vs. $225,000), total health care costs:($252,500 vs. $248,750). CONCLUSIONS: With this online compliance and cost-effectiveness software, the user can enter their own data to calculate and graph estimated QALYs, Life Years, drug costs, non-drug costs and total health expenditures. This web-based calculator has potential benefit as a basic tool for students, health professionals, and decision-makers.

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