Markov Transition Matrix Calculator:
Compliance Impact on Cost Effectiveness Analysis

(Beta Test -- For Demonstration Only)
[You can change transition values for "Compliant" and "NonCompliant Groups"
in white boxes below, then hit submit]
--- DATA ENTRY PAGE ---
Compliant Group and Drug Costs
Probability Transition Matrix
State of Next Cycle
State A State B State  CState D
State of
Current
Cycle
State A Each
Row Must Total 1.0
State B
State C
State D
State A State B State C State D
Utility for State
Cost for State
Number of Patients Maximum Cycles
NonCompliant Group and Drug Costs
Probability Transition Matrix
State of Next Cycle
State A State B State C State D
State of
Current
Cycle
State A Each
Row Must Total 1.0
State B
State C
State D
State A State B State C State D
Utility for State
Cost for State
Number of Patients Maximum Cycles
Same Each Group Same Each Group
Compliant Group and NonDrug Costs
Probability Transition Matrix
State of Next Cycle
State A State B State  CState D
State of
Current
Cycle
State A Each
Row Must Total 1.0
State B
State C
State D
State A State B State C State D
Utility for State
Cost for State
Number of Patients Maximum Cycles
Same All Groups Same All Groups
NonCompliant Group and NonDrug Costs
Probability Transition Matrix
State of Next Cycle
State A State B State C State D
State of
Current
Cycle
State A Each
Row Must Total 1.0
State B
State C
State D
State A State B State C State D
Utility for State
Cost for State
Number of Patients Maximum Cycles
Same Each Group Same Each Group



Sample Output -- Quardrants of Incremental Cost Utility
(Treatment minus Control Group)

Markov Matrix ICER Quadrants

Sample Output -- Markov Analysis Survival Curves

Markov Matrix - Survival Curves



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References:
-- Briggs A et al. Decision Modelling for Health Economic Evaluation. Oxford University Press, 2006.
-- Hunink M et al. Decision Making in Health and Medicine. Cambridge University Press, 2001.